PTGX

Protagonist Therapeutics, Inc Health Care Pharmaceutical Preparations Russell 3000
$144.85Close $9.1BMarket cap $75.95 – $158.6252-week range Nov 5, 2026Next report

Highlights

Strengths

  • In a stage-2 uptrend all 8 trend conditions pass
  • Leading the market RS 92 · stronger than 92% of stocks over 12 months

Cautions

  • Results soon Nov 5, 2026, in 4 days

Price

Filing Results Screen pick 52-week high and low Adjusted prices

Key figures

FY to Dec 31, 2025 · filed Aug 5, 2026
Off 12-month high 9%
1wk up 4.6% price change
1mo up 2.8% price change
12-month return up 86% market up 11% · its own up 78%
F-score — — Not assessed
Altman Z 100.95 Low risk
P/E — price / earnings
PEG — P/E / EPS growth
P/B 14.7× price / book
Earnings yield down 1.8% EBIT / enterprise value
Cheaper than 18% of the market · expensive
Revenue growth down 89% year on year
EPS growth — latest quarter
Sales growth up 3749% latest quarter
ROE down 20% return on equity
Free cash margin up 122% $56.1M FCF
D/E — long-term debt / equity
Net debt / EBITDA —
Interest cover —EBIT / interest

Trade setup

ATR% 3.6% $5.25 a day · 2×ATR $134.36
RS 92 / 99 vs the universe
Trend 8 / 8 trend template
Relative volume 0.5× vs 50-day average
Up/down volume 1.19 50 sessions
Implied move — no option chain · report Nov 5, 2026
Trend template · 8 of 8

Screen verdict

Did not qualify for any screen.

Warning signs

2 flagged
  • Shareholders diluted The share count rose 2.5% over the year, from 61m to 63m shares. Each existing share owns a smaller fraction of the company than it did a year ago.
  • Revenue shrinking Revenue fell 89.4% over the year, from $434.4M to $46.0M.
Last reported Aug 5, 2026
Results reaction Aug 5, 2026+8% vs market2 sessions after results

Financials

6 fiscal years · from filings
Revenue What customers paid the company over its fiscal year, before any cost, as filed in its annual report. The change is against the year before. Methodology $46.0M -89% on FY2024
$0 $500M FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · $28.6M FY2021 · $27.4M FY2022 · $26.6M FY2023 · $60.0M FY2024 · $434.4M FY2025 · $46.0M
Net income Profit left after every cost, interest and tax for the year. A column below the line is a loss. Methodology -$130.1M down to a loss
-$200M $0 $500M FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · -$66.2M FY2021 · -$125.6M FY2022 · -$127.4M FY2023 · -$79.0M FY2024 · $275.2M FY2025 · -$130.1M
Free cash flow Cash from running the business less what it spent on equipment and buildings: the cash a year actually left behind, which profit alone does not show. Not shown for banks and insurers, whose cash moves with their loans. Methodology $56.1M -69% on FY2024
-$200M $0 $200M FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · -$73.0M FY2021 · -$109.0M FY2022 · -$108.9M FY2023 · -$70.8M FY2024 · $182.8M FY2025 · $56.1M
Margins Each as a share of revenue. Gross: left after the direct cost of what was sold. Net: left after every cost. Free cash: free cash flow over revenue. A margin rising over years means the business keeps more of each dollar it sells. Methodology
  • Net -283%
  • Free cash 122%
-500% 0% 200% FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · Net -231% · Free cash -255% FY2021 · Net -459% · Free cash -398% FY2022 · Net -479% · Free cash -410% FY2023 · Net -132% · Free cash -118% FY2024 · Net 63% · Free cash 42% FY2025 · Net -283% · Free cash 122%
Cash and long-term debt Cash on the balance sheet at the year's end beside debt due after a year. Net cash is cash less that debt; net debt is the shortfall. Debt some filers do not tag shows as a gap, not as zero. Methodology
  • Cash
  • Long-term debt
$0 $200M FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · Cash $117.4M FY2021 · Cash $123.7M FY2022 · Cash $125.7M FY2023 · Cash $186.7M FY2024 · Cash $97.2M FY2025 · Cash $128.4M
Shares outstanding Shares in issue at the year's end. A rising count means each share owns a smaller slice of the company (stock pay, share sales); a falling one, buybacks. The chart's scale is fitted to the count, so a small change looks large: read the percentage. Methodology 62.58m +43.1% since FY2020
62.58m 43.75m FY20 FY21 FY22 FY23 FY24 FY25 FY2020 · 43.75m FY2021 · 47.84m FY2022 · 49.34m FY2023 · 57.71m FY2024 · 61.04m FY2025 · 62.58m
  FY2020Dec 31, 2020 FY2021Dec 31, 2021 FY2022Dec 31, 2022 FY2023Dec 31, 2023 FY2024Dec 31, 2024 FY2025Dec 31, 2025
Revenue $28.6M $27.4M $26.6M $60.0M $434.4M $46.0M
Operating income -$64.5M -$125.8M -$131.4M -$93.7M $252.8M -$158.1M
Net income -$66.2M -$125.6M -$127.4M -$79.0M $275.2M -$130.1M
Net margin -231% -459% -479% -132% 63% -283%
Earnings per share -$1.92 -$2.71 -$2.60 -$1.39 $4.23 -$2.05
Free cash flow -$73.0M -$109.0M -$108.9M -$70.8M $182.8M $56.1M
Free cash margin -255% -398% -410% -118% 42% 122%
Cash $117.4M $123.7M $125.7M $186.7M $97.2M $128.4M
Shareholders' equity $279.6M $300.0M $215.6M $336.7M $675.3M $614.7M
Shares outstanding 43.75m 47.84m 49.34m 57.71m 61.04m 62.58m

Filings

SEC EDGAR
FiledReportPeriod to Lag
Aug 5, 2026 Quarterly ↗ Jun 30, 2026 36d
May 5, 2026 Quarterly ↗ Mar 31, 2026 35d
Feb 25, 2026 Annual ↗ Dec 31, 2025 56d
Nov 6, 2025 Quarterly ↗ Sep 30, 2025 37d
Aug 6, 2025 Quarterly ↗ Jun 30, 2025 37d
May 6, 2025 Quarterly ↗ Mar 31, 2025 36d
Feb 21, 2025 Annual ↗ Dec 31, 2024 52d
Nov 7, 2024 Quarterly ↗ Sep 30, 2024 38d
Aug 6, 2024 Quarterly ↗ Jun 30, 2024 37d
May 7, 2024 Quarterly ↗ Mar 31, 2024 37d
Feb 27, 2024 Annual ↗ Dec 31, 2023 58d
Nov 2, 2023 Quarterly ↗ Sep 30, 2023 33d

Current reports

FiledDisclosed
Aug 5, 2026 Results · Regulation FD ↗
Jun 18, 2026 Director or officer change · Shareholder vote ↗
May 5, 2026 Results ↗
Feb 25, 2026 Results ↗
Jan 12, 2026 Regulation FD ↗
Nov 6, 2025 Results ↗
Aug 6, 2025 Results ↗
Jun 26, 2025 Shareholder vote ↗
May 6, 2025 Results ↗
Mar 20, 2025 Other events ↗
Mar 10, 2025 Other events ↗
Mar 3, 2025 Other events ↗